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Interferon gamma, an important marker of response to immune checkpoint blockade in non-small cell lung cancer and melanoma patients
BACKGROUND: Programmed death-ligand 1 (PD-L1) may be induced by oncogenic signals or can be upregulated via interferon gamma (IFN-γ). We have explored whether the expression of IFNG, the gene encoding IFN-γ, is associated with clinical response to the immune checkpoint blockade in non-small cell lun...
Autores principales: | Karachaliou, Niki, Gonzalez-Cao, Maria, Crespo, Guillermo, Drozdowskyj, Ana, Aldeguer, Erika, Gimenez-Capitan, Ana, Teixido, Cristina, Molina-Vila, Miguel Angel, Viteri, Santiago, De Los Llanos Gil, Maria, Algarra, Salvador Martin, Perez-Ruiz, Elisabeth, Marquez-Rodas, Ivan, Rodriguez-Abreu, Delvys, Blanco, Remedios, Puertolas, Teresa, Royo, Maria Angeles, Rosell, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784541/ https://www.ncbi.nlm.nih.gov/pubmed/29383037 http://dx.doi.org/10.1177/1758834017749748 |
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