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Development of a personalized therapeutic strategy for ERBB-gene-mutated cancers
BACKGROUND: The application of genomic technologies to patient tumor samples identified groups of signaling pathways which acquire activating mutations. Some cancers are dependent on these mutations and the aberrant proteins resulting from these mutations can be targeted by novel drugs which can era...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784557/ https://www.ncbi.nlm.nih.gov/pubmed/29383036 http://dx.doi.org/10.1177/1758834017746040 |