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Development of a personalized therapeutic strategy for ERBB-gene-mutated cancers

BACKGROUND: The application of genomic technologies to patient tumor samples identified groups of signaling pathways which acquire activating mutations. Some cancers are dependent on these mutations and the aberrant proteins resulting from these mutations can be targeted by novel drugs which can era...

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Detalles Bibliográficos
Autores principales: Milewska, Malgorzata, Cremona, Mattia, Morgan, Clare, O’Shea, John, Carr, Aoife, Vellanki, Sri HariKrishna, Hopkins, Ann M., Toomey, Sinead, Madden, Stephen F., Hennessy, Bryan T., Eustace, Alex J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784557/
https://www.ncbi.nlm.nih.gov/pubmed/29383036
http://dx.doi.org/10.1177/1758834017746040