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Immunogenicity of biologics in inflammatory bowel disease

Crohn’s disease and ulcerative colitis are chronic inflammatory disorders of the gastrointestinal tract. Treatment options include biologic therapies; however, a proportion of patients lose response to biologics, partly due to the formation of anti-drug antibodies (ADAbs). Concomitant immunosuppress...

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Detalles Bibliográficos
Autores principales: Vermeire, Séverine, Gils, Ann, Accossato, Paola, Lula, Sadiq, Marren, Amy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784568/
https://www.ncbi.nlm.nih.gov/pubmed/29383030
http://dx.doi.org/10.1177/1756283X17750355