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Lapatinib Inhibits Breast Cancer Cell Proliferation by Influencing PKM2 Expression

Pyruvate kinase type M2, which is expressed in multiple tumor cell types and plays a key role in aerobic glycolysis, also has nonglycolytic functions and can regulate transcription and cell proliferation. The results of this study show that epidermal growth factor receptor activation induces pyruvat...

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Detalles Bibliográficos
Autores principales: Guan, Mingxiu, Tong, Yingna, Guan, Minghua, Liu, Xiaobin, Wang, Meng, Niu, Ruifang, Zhang, Fei, Dong, Dong, Shao, Jie, Zhou, Yunli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784572/
https://www.ncbi.nlm.nih.gov/pubmed/29343208
http://dx.doi.org/10.1177/1533034617749418