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Lapatinib Inhibits Breast Cancer Cell Proliferation by Influencing PKM2 Expression
Pyruvate kinase type M2, which is expressed in multiple tumor cell types and plays a key role in aerobic glycolysis, also has nonglycolytic functions and can regulate transcription and cell proliferation. The results of this study show that epidermal growth factor receptor activation induces pyruvat...
Autores principales: | Guan, Mingxiu, Tong, Yingna, Guan, Minghua, Liu, Xiaobin, Wang, Meng, Niu, Ruifang, Zhang, Fei, Dong, Dong, Shao, Jie, Zhou, Yunli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784572/ https://www.ncbi.nlm.nih.gov/pubmed/29343208 http://dx.doi.org/10.1177/1533034617749418 |
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