Enhanced clinical-scale manufacturing of TCR transduced T-cells using closed culture system modules

BACKGROUND: Genetic engineering of T-cells to express specific T cell receptors (TCR) has emerged as a novel strategy to treat various malignancies. More widespread utilization of these types of therapies has been somewhat constrained by the lack of closed culture processes capable of expanding suff...

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Detalles Bibliográficos
Autores principales: Jin, Jianjian, Gkitsas, Nikolaos, Fellowes, Vicki S., Ren, Jiaqiang, Feldman, Steven A., Hinrichs, Christian S., Stroncek, David F., Highfill, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784598/
https://www.ncbi.nlm.nih.gov/pubmed/29368612
http://dx.doi.org/10.1186/s12967-018-1384-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784598/
https://www.ncbi.nlm.nih.gov/pubmed/29368612
http://dx.doi.org/10.1186/s12967-018-1384-z

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