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Deleterious genetic variants in ciliopathy genes increase risk of ritodrine-induced cardiac and pulmonary side effects

BACKGROUND: Ritodrine is a commonly used tocolytic to prevent preterm labour. However, it can cause unexpected serious adverse reactions, such as pulmonary oedema, pulmonary congestion, and tachycardia. It is unknown whether such adverse reactions are associated with pharmacogenomic variants in pati...

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Detalles Bibliográficos
Autores principales: Seo, Heewon, Kwon, Eun Jin, You, Young-Ah, Park, Yoomi, Min, Byung Joo, Yoo, Kyunghun, Hwang, Han-Sung, Kim, Ju Han, Kim, Young Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784607/
https://www.ncbi.nlm.nih.gov/pubmed/29368655
http://dx.doi.org/10.1186/s12920-018-0323-4