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Developmental dynamics of gene expression and alternative polyadenylation in the Caenorhabditis elegans germline

BACKGROUND: The 3′ untranslated regions (UTRs) of mRNAs play a major role in post-transcriptional regulation of gene expression. Selection of transcript cleavage and polyadenylation sites is a dynamic process that produces multiple transcript isoforms for the same gene within and across different ce...

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Detalles Bibliográficos
Autores principales: West, Sean M., Mecenas, Desirea, Gutwein, Michelle, Aristizábal-Corrales, David, Piano, Fabio, Gunsalus, Kristin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784609/
https://www.ncbi.nlm.nih.gov/pubmed/29368663
http://dx.doi.org/10.1186/s13059-017-1369-x