Network‐Wide Screen Identifies Variation of Novel Precise On‐Module Targets Using Conformational Modudaoism

Modular targeting is promising in drug research at the network level, but it is challenging to quantificationally identify the precise on‐modules. Based on a proposed Modudaoism (MD), we defined conserved MD (MDc) and varied MD (MDv) to quantitatively evaluate the conformational and energy variation...

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Detalles Bibliográficos
Autores principales: Li, Bing, Liu, Jun, Yu, Yanan, Wang, Pengqian, Zhang, Yingying, Ni, Xumin, Liu, Qiong, Zhang, Xiaoxu, Wang, Zhong, Wang, Yongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784734/
https://www.ncbi.nlm.nih.gov/pubmed/28925077
http://dx.doi.org/10.1002/psp4.12253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784734/
https://www.ncbi.nlm.nih.gov/pubmed/28925077
http://dx.doi.org/10.1002/psp4.12253

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