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Model‐Based Discovery and Development of Biopharmaceuticals: A Case Study of Mavrilimumab
Drug development is a lengthy, costly process with low probability of success. Biopharmaceuticals are highly specific molecules, with efficacy and safety closely tied to target biology and pharmacology. The “learning−predicting−confirming” continuum by translational and clinical modeling and simulat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784736/ https://www.ncbi.nlm.nih.gov/pubmed/28836356 http://dx.doi.org/10.1002/psp4.12245 |