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Model‐Based Discovery and Development of Biopharmaceuticals: A Case Study of Mavrilimumab

Drug development is a lengthy, costly process with low probability of success. Biopharmaceuticals are highly specific molecules, with efficacy and safety closely tied to target biology and pharmacology. The “learning−predicting−confirming” continuum by translational and clinical modeling and simulat...

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Detalles Bibliográficos
Autores principales: Wang, Bing, Wu, Chi‐Yuan, Jin, Denise, Vicini, Paolo, Roskos, Lorin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784736/
https://www.ncbi.nlm.nih.gov/pubmed/28836356
http://dx.doi.org/10.1002/psp4.12245