Cargando…
Model‐Based Discovery and Development of Biopharmaceuticals: A Case Study of Mavrilimumab
Drug development is a lengthy, costly process with low probability of success. Biopharmaceuticals are highly specific molecules, with efficacy and safety closely tied to target biology and pharmacology. The “learning−predicting−confirming” continuum by translational and clinical modeling and simulat...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784736/ https://www.ncbi.nlm.nih.gov/pubmed/28836356 http://dx.doi.org/10.1002/psp4.12245 |