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Multiplexed droplet single-cell RNA-sequencing using natural genetic variation

Droplet single-cell RNA-sequencing (dscRNA-seq) has enabled rapid, massively parallel profiling of transcriptomes. However, assessing differential expression across multiple individuals has been hampered by inefficient sample processing and technical batch effects. Here we describe a computational t...

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Detalles Bibliográficos
Autores principales: Kang, Hyun Min, Subramaniam, Meena, Targ, Sasha, Nguyen, Michelle, Maliskova, Lenka, McCarthy, Elizabeth, Wan, Eunice, Wong, Simon, Byrnes, Lauren, Lanata, Cristina, Gate, Rachel, Mostafavi, Sara, Marson, Alexander, Zaitlen, Noah, Criswell, Lindsey A, Ye, Chun Jimmie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784859/
https://www.ncbi.nlm.nih.gov/pubmed/29227470
http://dx.doi.org/10.1038/nbt.4042