Cargando…
Multiplexed droplet single-cell RNA-sequencing using natural genetic variation
Droplet single-cell RNA-sequencing (dscRNA-seq) has enabled rapid, massively parallel profiling of transcriptomes. However, assessing differential expression across multiple individuals has been hampered by inefficient sample processing and technical batch effects. Here we describe a computational t...
Autores principales: | Kang, Hyun Min, Subramaniam, Meena, Targ, Sasha, Nguyen, Michelle, Maliskova, Lenka, McCarthy, Elizabeth, Wan, Eunice, Wong, Simon, Byrnes, Lauren, Lanata, Cristina, Gate, Rachel, Mostafavi, Sara, Marson, Alexander, Zaitlen, Noah, Criswell, Lindsey A, Ye, Chun Jimmie |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784859/ https://www.ncbi.nlm.nih.gov/pubmed/29227470 http://dx.doi.org/10.1038/nbt.4042 |
Ejemplares similares
-
Transcriptomic analysis of immune cells in a multi-ethnic cohort of systemic lupus erythematosus patients identifies ethnicity- and disease-specific expression signatures
por: Andreoletti, Gaia, et al.
Publicado: (2021) -
DNA methylation 101: what is important to know about DNA methylation and its role in SLE risk and disease heterogeneity
por: Lanata, Cristina M, et al.
Publicado: (2018) -
Selection and explosive growth alter genetic architecture and hamper the detection of causal rare variants
por: Uricchio, Lawrence H., et al.
Publicado: (2016) -
Functional CRISPR dissection of gene networks controlling human regulatory T cell identity
por: Schumann, Kathrin, et al.
Publicado: (2020) -
GBAT: a gene-based association test for robust detection of trans-gene regulation
por: Liu, Xuanyao, et al.
Publicado: (2020)