Genomic locus modulating corneal thickness in the mouse identifies POU6F2 as a potential risk of developing glaucoma

Central corneal thickness (CCT) is one of the most heritable ocular traits and it is also a phenotypic risk factor for primary open angle glaucoma (POAG). The present study uses the BXD Recombinant Inbred (RI) strains to identify novel quantitative trait loci (QTLs) modulating CCT in the mouse with...

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Detalles Bibliográficos
Autores principales: King, Rebecca, Struebing, Felix L., Li, Ying, Wang, Jiaxing, Koch, Allison Ashley, Cooke Bailey, Jessica N., Gharahkhani, Puya, MacGregor, Stuart, Allingham, R. Rand, Hauser, Michael A., Wiggs, Janey L., Geisert, Eldon E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784889/
https://www.ncbi.nlm.nih.gov/pubmed/29370175
http://dx.doi.org/10.1371/journal.pgen.1007145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784889/
https://www.ncbi.nlm.nih.gov/pubmed/29370175
http://dx.doi.org/10.1371/journal.pgen.1007145

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