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Development and evaluation of Chitosan nanoparticles based dry powder inhalation formulations of Prothionamide

Prothionamide (PTH), a second line antitubercular drug is used to administer in conventional oral route. However, its unpredictable absorption and frequent administration limit its use. An alternate approach was thought of administering PTH through pulmonary route in a form of nanoparticles, which c...

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Detalles Bibliográficos
Autores principales: Debnath, Sujit Kumar, Saisivam, Srinivasan, Debanth, Monalisha, Omri, Abdelwahab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784924/
https://www.ncbi.nlm.nih.gov/pubmed/29370192
http://dx.doi.org/10.1371/journal.pone.0190976