Adjuvanting influenza hemagglutinin vaccine with a human pulmonary surfactant-mimicking synthetic compound SF-10 induces local and systemic cell-mediated immunity in mice

We reported previously that intranasal instillation of a synthetic human pulmonary surfactant with a carboxy vinyl polymer as a viscosity improver, named SF-10, shows potent adjuvanticity for humoral immunity in mice and cynomolgus monkeys. SF-10 effectively induces influenza hemagglutinin vaccine (...

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Detalles Bibliográficos
Autores principales: Kim, Hyejin, Kimoto, Takashi, Sakai, Satoko, Takahashi, Etsuhisa, Kido, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784949/
https://www.ncbi.nlm.nih.gov/pubmed/29370185
http://dx.doi.org/10.1371/journal.pone.0191133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784949/
https://www.ncbi.nlm.nih.gov/pubmed/29370185
http://dx.doi.org/10.1371/journal.pone.0191133

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