The histone demethylase LSD1 regulates inner ear progenitor differentiation through interactions with Pax2 and the NuRD repressor complex

The histone demethylase LSD1 plays a pivotal role in cellular differentiation, particularly in silencing lineage-specific genes. However, little is known about how LSD1 regulates neurosensory differentiation in the inner ear. Here we show that LSD1 interacts directly with the transcription factor Pa...

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Detalles Bibliográficos
Autores principales: Patel, Dharmeshkumar, Shimomura, Atsushi, Majumdar, Sreeparna, Holley, Matthew C., Hashino, Eri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784988/
https://www.ncbi.nlm.nih.gov/pubmed/29370269
http://dx.doi.org/10.1371/journal.pone.0191689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5784988/
https://www.ncbi.nlm.nih.gov/pubmed/29370269
http://dx.doi.org/10.1371/journal.pone.0191689

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