PAN-811 prevents chemotherapy-induced cognitive impairment and preserves neurogenesis in the hippocampus of adult rats

Chemotherapy-induced cognitive impairment (CICI) occurs in a substantial proportion of treated cancer patients, with no drug currently available for its therapy. This study investigated whether PAN-811, a ribonucleotide reductase inhibitor, can reduce cognitive impairment and related suppression of...

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Detalles Bibliográficos
Autores principales: Jiang, Zhi-Gang, Winocur, Gordon, Wojtowicz, J. Martin, Shevtsova, Olga, Fuller, Steven, Ghanbari, Hossein A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785016/
https://www.ncbi.nlm.nih.gov/pubmed/29370277
http://dx.doi.org/10.1371/journal.pone.0191866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785016/
https://www.ncbi.nlm.nih.gov/pubmed/29370277
http://dx.doi.org/10.1371/journal.pone.0191866

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