Cargando…

AKAP200 promotes Notch stability by protecting it from Cbl/lysosome-mediated degradation in Drosophila melanogaster

AKAP200 is a Drosophila melanogaster member of the “A Kinase Associated Protein” family of scaffolding proteins, known for their role in the spatial and temporal regulation of Protein Kinase A (PKA) in multiple signaling contexts. Here, we demonstrate an unexpected function of AKAP200 in promoting N...

Descripción completa

Detalles Bibliográficos
Autores principales: Bala Tannan, Neeta, Collu, Giovanna, Humphries, Ashley C., Serysheva, Ekatherina, Weber, Ursula, Mlodzik, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785023/
https://www.ncbi.nlm.nih.gov/pubmed/29309414
http://dx.doi.org/10.1371/journal.pgen.1007153