SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells

Single-stranded oligonucleotides (ssOligos) are efficiently taken up by living cells without the use of transfection reagents. This phenomenon called ‘gymnosis’ enables the sequence-specific silencing of target genes in various types of cells. Several antisense ssOligos are used for the treatment of...

Descripción completa

Detalles Bibliográficos
Autores principales: Takahashi, Masayuki, Contu, Viorica Raluca, Kabuta, Chihana, Hase, Katsunori, Fujiwara, Yuuki, Wada, Keiji, Kabuta, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785214/
https://www.ncbi.nlm.nih.gov/pubmed/28277980
http://dx.doi.org/10.1080/15476286.2017.1302641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785214/
https://www.ncbi.nlm.nih.gov/pubmed/28277980
http://dx.doi.org/10.1080/15476286.2017.1302641

Ejemplares similares