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A compensatory mutagenesis study of a conserved hairpin in the M gene segment of influenza A virus shows its role in virus replication

RNA structures are increasingly recognized to be of importance during influenza A virus replication. Here, we investigated a predicted conserved hairpin in the M gene segment (nt 967-994) within the region of the vRNA 5′ packaging signal. The existence of this RNA structure and its possible role in...

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Detalles Bibliográficos
Autores principales: Spronken, M. I., van de Sandt, C. E., de Jongh, E. P., Vuong, O., van der Vliet, S., Bestebroer, T. M., Olsthoorn, R. C. L., Rimmelzwaan, G. F., Fouchier, R.A. M., Gultyaev, A. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785231/
https://www.ncbi.nlm.nih.gov/pubmed/28662365
http://dx.doi.org/10.1080/15476286.2017.1338243