Atomic structure of the eukaryotic intramembrane Ras methyltransferase ICMT

The maturation of Ras GTPases, and ~200 other cellular CaaX proteins, involves three enzymatic steps: addition of a farnesyl or geranylgeranyl prenyl lipid to the cysteine (C) in the C-terminal CaaX motif, proteolytic cleavage of the aaX residues, and methylation of the exposed prenylcysteine residu...

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Detalles Bibliográficos
Autores principales: Diver, Melinda M., Pedi, Leanne, Koide, Akiko, Koide, Shohei, Long, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785467/
https://www.ncbi.nlm.nih.gov/pubmed/29342140
http://dx.doi.org/10.1038/nature25439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785467/
https://www.ncbi.nlm.nih.gov/pubmed/29342140
http://dx.doi.org/10.1038/nature25439

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