Immunization with Transgenic Rodent Malaria Parasites Expressing Pfs25 Induces Potent Transmission-Blocking Activity

An anti-malarial transmission blocking vaccine (TBV) would be an important tool for disease control or elimination, though current candidates have failed to induce high efficacy in clinical studies. The ookinete surface protein P25 is a primary target for TBV development, but heterologous expression...

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Detalles Bibliográficos
Autores principales: Sala, K. A., Angrisano, F., Da, D. F., Taylor, I. J., Churcher, T. S., Blagborough, A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785477/
https://www.ncbi.nlm.nih.gov/pubmed/29371619
http://dx.doi.org/10.1038/s41598-017-18831-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785477/
https://www.ncbi.nlm.nih.gov/pubmed/29371619
http://dx.doi.org/10.1038/s41598-017-18831-8

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