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Immunization with Transgenic Rodent Malaria Parasites Expressing Pfs25 Induces Potent Transmission-Blocking Activity
An anti-malarial transmission blocking vaccine (TBV) would be an important tool for disease control or elimination, though current candidates have failed to induce high efficacy in clinical studies. The ookinete surface protein P25 is a primary target for TBV development, but heterologous expression...
Autores principales: | Sala, K. A., Angrisano, F., Da, D. F., Taylor, I. J., Churcher, T. S., Blagborough, A. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785477/ https://www.ncbi.nlm.nih.gov/pubmed/29371619 http://dx.doi.org/10.1038/s41598-017-18831-8 |
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