In silico profiling of systemic effects of drugs to predict unexpected interactions

Identifying unexpected drug interactions is an essential step in drug development. Most studies focus on predicting whether a drug pair interacts or is effective on a certain disease without considering the mechanism of action (MoA). Here, we introduce a novel method to infer effects and interaction...

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Detalles Bibliográficos
Autores principales: Yoo, Sunyong, Noh, Kyungrin, Shin, Moonshik, Park, Junseok, Lee, Kwang-Hyung, Nam, Hojung, Lee, Doheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785495/
https://www.ncbi.nlm.nih.gov/pubmed/29371651
http://dx.doi.org/10.1038/s41598-018-19614-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785495/
https://www.ncbi.nlm.nih.gov/pubmed/29371651
http://dx.doi.org/10.1038/s41598-018-19614-5

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