Degradation routes of trafficking-defective VLDLR mutants associated with Dysequilibrium syndrome

Low density lipoprotein receptor (LDLR) family members are involved in signaling in the developing brain. Previously we have reported that missense mutations in the Very Low Density Lipoprotein Receptor gene (VLDLR), causing Dysequilibrium syndrome (DES), disrupt ligand-binding, due to endoplasmic r...

Descripción completa

Detalles Bibliográficos
Autores principales: Kizhakkedath, Praseetha, John, Anne, Al-Gazali, Lihadh, Ali, Bassam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785505/
https://www.ncbi.nlm.nih.gov/pubmed/29371607
http://dx.doi.org/10.1038/s41598-017-19053-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785505/
https://www.ncbi.nlm.nih.gov/pubmed/29371607
http://dx.doi.org/10.1038/s41598-017-19053-8

Ejemplares similares