PD-L1 reverses depigmentation in Pmel-1 vitiligo mice by increasing the abundance of Tregs in the skin

Programmed cell death 1 ligand 1 (PD-L1) is a ligand of programmed cell death 1 (PD-1) that functions as an immune checkpoint by down-regulating immune responses. To determine whether PD-L1 is a therapy target in vitiligo treatment, Pmel-1 vitiligo mice were treated with a PD-L1 fusion protein. Trea...

Descripción completa

Detalles Bibliográficos
Autores principales: Miao, Xiao, Xu, Rong, Fan, Bin, Chen, Jie, Li, Xin, Mao, Weiwei, Hua, Shengyuan, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785514/
https://www.ncbi.nlm.nih.gov/pubmed/29371688
http://dx.doi.org/10.1038/s41598-018-19407-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785514/
https://www.ncbi.nlm.nih.gov/pubmed/29371688
http://dx.doi.org/10.1038/s41598-018-19407-w

Ejemplares similares