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Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts

Conflicts between replication and transcription machineries represent a major source of genomic instability and cells have evolved strategies to prevent such conflicts. However, little is known regarding how cells cope with sudden increases of transcription while replicating. Here, we report the exi...

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Detalles Bibliográficos
Autores principales: Duch, Alba, Canal, Berta, Barroso, Sonia I., García-Rubio, María, Seisenbacher, Gerhard, Aguilera, Andrés, de Nadal, Eulàlia, Posas, Francesc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785523/
https://www.ncbi.nlm.nih.gov/pubmed/29371596
http://dx.doi.org/10.1038/s41467-017-02756-x