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Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts
Conflicts between replication and transcription machineries represent a major source of genomic instability and cells have evolved strategies to prevent such conflicts. However, little is known regarding how cells cope with sudden increases of transcription while replicating. Here, we report the exi...
Autores principales: | Duch, Alba, Canal, Berta, Barroso, Sonia I., García-Rubio, María, Seisenbacher, Gerhard, Aguilera, Andrés, de Nadal, Eulàlia, Posas, Francesc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785523/ https://www.ncbi.nlm.nih.gov/pubmed/29371596 http://dx.doi.org/10.1038/s41467-017-02756-x |
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