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Generation of Induced Progenitor-like Cells from Mature Epithelial Cells Using Interrupted Reprogramming

A suitable source of progenitor cells is required to attenuate disease or affect cure. We present an “interrupted reprogramming” strategy to generate “induced progenitor-like (iPL) cells” using carefully timed expression of induced pluripotent stem cell reprogramming factors (Oct4, Sox2, Klf4, and c...

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Detalles Bibliográficos
Autores principales: Guo, Li, Karoubi, Golnaz, Duchesneau, Pascal, Shutova, Maria V., Sung, Hoon-Ki, Tonge, Peter, Bear, Christine, Rogers, Ian, Nagy, Andras, Waddell, Thomas K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785620/
https://www.ncbi.nlm.nih.gov/pubmed/29198829
http://dx.doi.org/10.1016/j.stemcr.2017.10.022