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RHOA GTPase Controls YAP-Mediated EREG Signaling in Small Intestinal Stem Cell Maintenance

RHOA, a founding member of the Rho GTPase family, is critical for actomyosin dynamics, polarity, and morphogenesis in response to developmental cues, mechanical stress, and inflammation. In murine small intestinal epithelium, inducible RHOA deletion causes a loss of epithelial polarity, with disrupt...

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Detalles Bibliográficos
Autores principales: Liu, Ming, Zhang, Zheng, Sampson, Leesa, Zhou, Xuan, Nalapareddy, Kodandaramireddy, Feng, Yuxin, Akunuru, Shailaja, Melendez, Jaime, Davis, Ashley Kuenzi, Bi, Feng, Geiger, Hartmut, Xin, Mei, Zheng, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785633/
https://www.ncbi.nlm.nih.gov/pubmed/29129684
http://dx.doi.org/10.1016/j.stemcr.2017.10.004