Serine 347 Phosphorylation by JNKs Negatively Regulates OCT4 Protein Stability in Mouse Embryonic Stem Cells

The POU transcription factor OCT4 is critical for maintaining the undifferentiated state of embryonic stem cells (ESCs) and generating induced pluripotent stem cells (iPSCs), but its precise mechanisms of action remain poorly understood. Here, we investigated the role of OCT4 phosphorylation in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Bae, Ki Beom, Yu, Dong Hoon, Lee, Kun Yeong, Yao, Ke, Ryu, Joohyun, Lim, Do Young, Zykova, Tatyana A., Kim, Myoung Ok, Bode, Ann M., Dong, Zigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785688/
https://www.ncbi.nlm.nih.gov/pubmed/29153991
http://dx.doi.org/10.1016/j.stemcr.2017.10.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785688/
https://www.ncbi.nlm.nih.gov/pubmed/29153991
http://dx.doi.org/10.1016/j.stemcr.2017.10.017

Ejemplares similares