PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease

Alzheimer's disease (AD) is a common neurodegenerative disorder and the leading cause of cognitive impairment. Due to insufficient understanding of the disease mechanisms, there are no efficient therapies for AD. Most studies have focused on neuronal cells, but astrocytes have also been suggest...

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Detalles Bibliográficos
Autores principales: Oksanen, Minna, Petersen, Andrew J., Naumenko, Nikolay, Puttonen, Katja, Lehtonen, Šárka, Gubert Olivé, Max, Shakirzyanova, Anastasia, Leskelä, Stina, Sarajärvi, Timo, Viitanen, Matti, Rinne, Juha O., Hiltunen, Mikko, Haapasalo, Annakaisa, Giniatullin, Rashid, Tavi, Pasi, Zhang, Su-Chun, Kanninen, Katja M., Hämäläinen, Riikka H., Koistinaho, Jari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785689/
https://www.ncbi.nlm.nih.gov/pubmed/29153989
http://dx.doi.org/10.1016/j.stemcr.2017.10.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785689/
https://www.ncbi.nlm.nih.gov/pubmed/29153989
http://dx.doi.org/10.1016/j.stemcr.2017.10.016

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