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Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability

Alzheimer's disease (AD) induces memory and cognitive impairment in the absence of motor and sensory deficits during its early and middle course. A major unresolved question is the basis for this selective neuronal vulnerability. Aβ, which plays a central role in AD pathogenesis, is generated t...

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Detalles Bibliográficos
Autores principales: Muratore, Christina R., Zhou, Constance, Liao, Meichen, Fernandez, Marty A., Taylor, Walter M., Lagomarsino, Valentina N., Pearse, Richard V., Rice, Heather C., Negri, Joseph M., He, Amy, Srikanth, Priya, Callahan, Dana G., Shin, Taehwan, Zhou, Monica, Bennett, David A., Noggle, Scott, Love, J. Christopher, Selkoe, Dennis J., Young-Pearse, Tracy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785690/
https://www.ncbi.nlm.nih.gov/pubmed/29153990
http://dx.doi.org/10.1016/j.stemcr.2017.10.015