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Recent Progress in CFTR Interactome Mapping and Its Importance for Cystic Fibrosis

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is a chloride channel found in secretory epithelia with a plethora of known interacting proteins. Mutations in the CFTR gene cause cystic fibrosis (CF), a disease that leads to progressive respiratory illness and other complications of pheno...

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Detalles Bibliográficos
Autores principales: Lim, Sang Hyun, Legere, Elizabeth-Ann, Snider, Jamie, Stagljar, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785726/
https://www.ncbi.nlm.nih.gov/pubmed/29403380
http://dx.doi.org/10.3389/fphar.2017.00997