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TRIM28 and Interacting KRAB-ZNFs Control Self-Renewal of Human Pluripotent Stem Cells through Epigenetic Repression of Pro-differentiation Genes

Reprogramming to induced pluripotent stem cells (iPSCs) and differentiation of pluripotent stem cells (PSCs) are regulated by epigenetic machinery. Tripartite motif protein 28 (TRIM28), a universal mediator of Krüppel-associated box domain zinc fingers (KRAB-ZNFs), is known to regulate both processe...

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Detalles Bibliográficos
Autores principales: Oleksiewicz, Urszula, Gładych, Marta, Raman, Ayush T., Heyn, Holger, Mereu, Elisabetta, Chlebanowska, Paula, Andrzejewska, Anastazja, Sozańska, Barbara, Samant, Neha, Fąk, Katarzyna, Auguścik, Paulina, Kosiński, Marcin, Wróblewska, Joanna P., Tomczak, Katarzyna, Kulcenty, Katarzyna, Płoski, Rafał, Biecek, Przemysław, Esteller, Manel, Shah, Parantu K., Rai, Kunal, Wiznerowicz, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785758/
https://www.ncbi.nlm.nih.gov/pubmed/29198826
http://dx.doi.org/10.1016/j.stemcr.2017.10.031