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Endurance training remodels sperm-borne small RNA expression and methylation at neurological gene hotspots

Remodeling of the sperm epigenome by lifestyle factors before conception could account for altered metabolism in the next generation offspring. Here, we hypothesized that endurance training changes the epigenome of human spermatozoa. Using small RNA (sRNA) sequencing and reduced representation bisul...

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Detalles Bibliográficos
Autores principales: Ingerslev, Lars R., Donkin, Ida, Fabre, Odile, Versteyhe, Soetkin, Mechta, Mie, Pattamaprapanont, Pattarawan, Mortensen, Brynjulf, Krarup, Nikolaj Thure, Barrès, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785820/
https://www.ncbi.nlm.nih.gov/pubmed/29416570
http://dx.doi.org/10.1186/s13148-018-0446-7