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Endurance training remodels sperm-borne small RNA expression and methylation at neurological gene hotspots
Remodeling of the sperm epigenome by lifestyle factors before conception could account for altered metabolism in the next generation offspring. Here, we hypothesized that endurance training changes the epigenome of human spermatozoa. Using small RNA (sRNA) sequencing and reduced representation bisul...
Autores principales: | Ingerslev, Lars R., Donkin, Ida, Fabre, Odile, Versteyhe, Soetkin, Mechta, Mie, Pattamaprapanont, Pattarawan, Mortensen, Brynjulf, Krarup, Nikolaj Thure, Barrès, Romain |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785820/ https://www.ncbi.nlm.nih.gov/pubmed/29416570 http://dx.doi.org/10.1186/s13148-018-0446-7 |
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