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Establishment and genomic characterizations of patient-derived esophageal squamous cell carcinoma xenograft models using biopsies for treatment optimization

BACKGROUND: Squamous cell carcinoma is the dominant type of esophageal cancer in China with many patients initially diagnosed at advanced stage. Patient-derived xenografts (PDX) models have been developed to be an important platform for preclinical research. This study aims to establish and characte...

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Detalles Bibliográficos
Autores principales: Zou, Jianling, Liu, Ying, Wang, Jingyuan, Liu, Zhentao, Lu, Zhihao, Chen, Zuhua, Li, Zhongwu, Dong, Bin, Huang, Wenwen, Li, Yanyan, Gao, Jing, Shen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785825/
https://www.ncbi.nlm.nih.gov/pubmed/29370817
http://dx.doi.org/10.1186/s12967-018-1379-9