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PML: Regulation and multifaceted function beyond tumor suppression

Promyelocytic leukemia protein (PML) was originally identified as a fusion partner of retinoic acid receptor alpha in acute promyelocytic leukemia patients with the (15;17) chromosomal translocation, giving rise to PML–RARα and RARα–PML fusion proteins. A body of evidence indicated that PML possesse...

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Detalles Bibliográficos
Autores principales: Hsu, Kuo-Sheng, Kao, Hung-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785837/
https://www.ncbi.nlm.nih.gov/pubmed/29416846
http://dx.doi.org/10.1186/s13578-018-0204-8