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A mechanism-based pharmacokinetic model of fenofibrate for explaining increased drug absorption after food consumption

BACKGROUND: Oral administration of drugs is convenient and shows good compliance but it can be affected by many factors in the gastrointestinal (GI) system. Consumption of food is one of the major factors affecting the GI system and consequently the absorption of drugs. The aim of this study was to...

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Detalles Bibliográficos
Autores principales: Back, Hyun-moon, Song, Byungjeong, Pradhan, Sudeep, Chae, Jung-woo, Han, Nayoung, Kang, Wonku, Chang, Min Jung, Zheng, Jiao, Kwon, Kwang-il, Karlsson, Mats O., Yun, Hwi-yeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785874/
https://www.ncbi.nlm.nih.gov/pubmed/29370865
http://dx.doi.org/10.1186/s40360-018-0194-5