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A report of nine cases and review of the literature of infertile men carrying balanced translocations involving chromosome 5

BACKGROUND: Balanced translocations may cause the loss of genetic material at the breakpoints and may result in failure of spermatogenesis. However, carriers of reciprocal translocation may naturally conceive. Genetic counseling of male carriers of translocations remains challenging. This study expl...

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Detalles Bibliográficos
Autores principales: Zhang, Hong-Guo, Wang, Rui-Xue, Pan, Yuan, Zhang, Han, Li, Lei-Lei, Zhu, Hai-Bo, Liu, Rui-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785882/
https://www.ncbi.nlm.nih.gov/pubmed/29416565
http://dx.doi.org/10.1186/s13039-018-0360-x