Restrained management of copper level enhances the antineoplastic activity of imatinib in vitro and in vivo

The present study was designed to investigate if elevated copper level can be targeted to enhance the efficacy of a significant anticancer drug, imatinib (ITB). The antineoplastic activity of this drug was assessed in the HepG2, HEK-293, MCF-7 and MDA-MD-231 cells targeting elevated copper level as...

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Detalles Bibliográficos
Autores principales: Hassan, Iftekhar, Khan, Azmat Ali, Aman, Shazia, Qamar, Wajhul, Ebaid, Hossam, Al-Tamimi, Jameel, Alhazza, Ibrahim M., Rady, Ahmed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786010/
https://www.ncbi.nlm.nih.gov/pubmed/29374195
http://dx.doi.org/10.1038/s41598-018-19410-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786010/
https://www.ncbi.nlm.nih.gov/pubmed/29374195
http://dx.doi.org/10.1038/s41598-018-19410-1

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