Cargando…

Restrained management of copper level enhances the antineoplastic activity of imatinib in vitro and in vivo

The present study was designed to investigate if elevated copper level can be targeted to enhance the efficacy of a significant anticancer drug, imatinib (ITB). The antineoplastic activity of this drug was assessed in the HepG2, HEK-293, MCF-7 and MDA-MD-231 cells targeting elevated copper level as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hassan, Iftekhar, Khan, Azmat Ali, Aman, Shazia, Qamar, Wajhul, Ebaid, Hossam, Al-Tamimi, Jameel, Alhazza, Ibrahim M., Rady, Ahmed M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786010/ https://www.ncbi.nlm.nih.gov/pubmed/29374195 http://dx.doi.org/10.1038/s41598-018-19410-1

Ejemplares similares

Disulfiram Enhances the Antineoplastic Activity and Sensitivity of Murine Hepatocellular Carcinoma to 5-FU via Redox Management
por: Hassan, Iftekhar, et al.
Publicado: (2023)

Copper Mediates Anti-Inflammatory and Antifibrotic Activity of Gleevec in Hepatocellular Carcinoma-Induced Male Rats
por: Hassan, Iftekhar, et al.
Publicado: (2019)

The Alleviative Effect of Vitamin B(2) on Potassium Bromate-Induced Hepatotoxicity in Male Rats
por: Hassan, Iftekhar, et al.
Publicado: (2020)

Silver Nanoparticles Decorated with Curcumin Enhance the Efficacy of Metformin in Diabetic Rats via Suppression of Hepatotoxicity
por: Hassan, Iftekhar, et al.
Publicado: (2023)

Samsum ant venom modulates the immune response and redox status at the acute toxic dose in vivo
por: Ebaid, Hossam, et al.
Publicado: (2019)

Diabetes-Mediated Toxicity Resulted in the Expression of CD80 and CD86 on Neutrophils after Delayed Wound Healing in Male Rats
por: Ebaid, Hossam, et al.
Publicado: (2020)

Zinc Oxide Nanoparticles Blunt Potassium-Bromate-Induced Renal Toxicity by Reinforcing the Redox System
por: Alhazza, Ibrahim M., et al.
Publicado: (2023)

Antioxidant Bioactivity of Samsum Ant (Pachycondyla sennaarensis) Venom Protects against CCL(4)-Induced Nephrotoxicity in Mice
por: Ebaid, Hossam, et al.
Publicado: (2014)

Potential effects of samsum ant, Brachyponera sennaarensis, venom on TNF-α/NF-κB mediated inflammation in CCL4-toxicity in vivo
por: Al-Tamimi, Jameel, et al.
Publicado: (2016)

Efficacy of a Methanolic Extract of Adansonia digitata Leaf in Alleviating Hyperglycemia, Hyperlipidemia, and Oxidative Stress of Diabetic Rats
por: Ebaid, Hossam, et al.
Publicado: (2019)

Camel milk peptide improves wound healing in diabetic rats by orchestrating the redox status and immune response
por: Ebaid, Hossam, et al.
Publicado: (2015)

Erratum to: Camel milk peptide improves wound healing in diabetic rats by orchestrating the redox status and immune response
por: Ebaid, Hossam, et al.
Publicado: (2017)

Thymoquinone ameliorates Pachycondyla sennaarensis venom-induced acute toxic shock in male rats
por: Alhazza, Ibrahim M., et al.
Publicado: (2019)

Folic acid and melatonin mitigate diabetic nephropathy in rats via inhibition of oxidative stress
por: Ebaid, Hossam, et al.
Publicado: (2020)

Bioactive Tryptophan-Based Copper Complex with Auxiliary β-Carboline Spectacle Potential on Human Breast Cancer Cells: In Vitro and In Vivo Studies
por: Alharbi, Walaa, et al.
Publicado: (2021)

Potential effects of the combination of nicotinamide, vitamin B2 and vitamin C on oxidative-mediated hepatotoxicity induced by thioacetamide
por: Bashandy, Samir A. E., et al.
Publicado: (2018)

Protective Effect of Daidzein against Diethylnitrosamine/Carbon Tetrachloride-Induced Hepatocellular Carcinoma in Male Rats
por: Bashandy, Samir A. E., et al.
Publicado: (2023)

Zinc improves the immune function and the proliferation of lymphocytes in Cadmium-treated rats
por: Ebaid, Hossam, et al.
Publicado: (2014)

Folic acid and melatonin ameliorate carbon tetrachloride-induced hepatic injury, oxidative stress and inflammation in rats
por: Ebaid, Hossam, et al.
Publicado: (2013)

Melatonin Alleviated Potassium Dichromate-Induced Oxidative Stress and Reprotoxicity in Male Rats
por: Bashandy, Samir A. E., et al.
Publicado: (2021)

Antioxidant Potential of Spirulina platensis Mitigates Oxidative Stress and Reprotoxicity Induced by Sodium Arsenite in Male Rats
por: Bashandy, Samir A. E., et al.
Publicado: (2016)

Nephroprotective Effect of Pleurotus ostreatus and Agaricus bisporus Extracts and Carvedilol on Ethylene Glycol-Induced Urolithiasis: Roles of NF-κB, p53, Bcl-2, Bax and Bak
por: Ahmed, Osama M., et al.
Publicado: (2020)

Riboflavin Arrests Cisplatin-Induced Neurotoxicity by Ameliorating Cellular Damage in Dorsal Root Ganglion Cells
por: Salman, Maria, et al.
Publicado: (2015)

Antidiabetic Potency, Antioxidant Effects, and Mode of Actions of Citrus reticulata Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin in Nicotinamide/Streptozotocin-Induced Wistar Diabetic Rats
por: Ali, Alaa M., et al.
Publicado: (2020)

Effect of zinc on cadmium induced oxidative stress: an in vivo study
por: Alhazza, Ibrahim
Publicado: (2015)

Antineoplastic Effects of Ankaferd Hemostat
por: Malkan, Umit Yavuz, et al.
Publicado: (2022)

Bactericides Based on Copper Nanoparticles Restrain Growth of Important Plant Pathogens
por: Varympopi, Adamantia, et al.
Publicado: (2020)

Development and In Vitro and In Vivo Evaluation of an Antineoplastic Copper(II) Compound (Casiopeina III-ia) Loaded in Nonionic Vesicles Using Quality by Design
por: Aguilar-Jiménez, Zenayda, et al.
Publicado: (2022)

Promotion of immune and glycaemic functions in streptozotocin-induced diabetic rats treated with un-denatured camel milk whey proteins
por: Ebaid, Hossam
Publicado: (2014)

Neutrophil depletion in the early inflammatory phase delayed cutaneous wound healing in older rats: improvements due to the use of un-denatured camel whey protein
por: Ebaid, Hossam
Publicado: (2014)

BCc1, the novel antineoplastic nanocomplex, showed potent anticancer effects in vitro and in vivo
por: Kalanaky, Somayeh, et al.
Publicado: (2015)

In Vitro Antineoplastic and Antiviral Activity and In Vivo Toxicity of Geum urbanum L. Extracts
por: Zaharieva, Maya M., et al.
Publicado: (2021)

Antineoplastic activity of idazoxan hydrochloride
por: Eilon, G. F., et al.
Publicado: (2009)

Resistance to antineoplastic drugs
por: Twentyman, Peter
Publicado: (1990)

Pharmacological Effects of Grape Leaf Extract Reduce Eimeriosis-Induced Inflammation, Oxidative Status Change, and Goblet Cell Response in the Jejunum of Mice
por: Murshed, Mutee, et al.
Publicado: (2023)

In vitro antineoplastic activity in triple-negative breast cancer cell line and in vivo
por: Madeira, Klesia, et al.
Publicado: (2014)

Preparation, In Vivo Administration, Dose-Limiting Toxicities, and Antineoplastic Activity of Cytochalasin B
por: Trendowski, Matthew, et al.
Publicado: (2015)

Preclinical Study of Antineoplastic Sinoporphyrin Sodium-PDT via In Vitro and In Vivo Models
por: Shi, Rui, et al.
Publicado: (2017)

Luteolin-Loaded Elastic Liposomes for Transdermal Delivery to Control Breast Cancer: In Vitro and Ex Vivo Evaluations
por: Altamimi, Mohammad A., et al.
Publicado: (2021)

Impact of imatinib on the pharmacokinetics and in vivo efficacy of etoposide and/or ifosfamide
por: Rezaï, Keyvan, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_1m4743opi7830nlmlukr2vi3qj