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Mutational landscape of RNA-binding proteins in human cancers

RNA Binding Proteins (RBPs) are a class of post-transcriptional regulatory molecules which are increasingly documented to be dysfunctional in cancer genomes. However, our current understanding of these alterations is limited. Here, we delineate the mutational landscape of ∼1300 RBPs in ∼6000 cancer...

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Detalles Bibliográficos
Autores principales: Neelamraju, Yaseswini, Gonzalez-Perez, Abel, Bhat-Nakshatri, Poornima, Nakshatri, Harikrishna, Janga, Sarath Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786023/
https://www.ncbi.nlm.nih.gov/pubmed/29023197
http://dx.doi.org/10.1080/15476286.2017.1391436