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Modulation of oncogenic miRNA biogenesis using functionalized polyamines

MicroRNAs are key factors in the regulation of gene expression and their deregulation has been directly linked to various pathologies such as cancer. The use of small molecules to tackle the overexpression of oncogenic miRNAs has proved its efficacy and holds the promise for therapeutic applications...

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Detalles Bibliográficos
Autores principales: Staedel, Cathy, Tran, Thi Phuong Anh, Giraud, Julie, Darfeuille, Fabien, Di Giorgio, Audrey, Tourasse, Nicolas J., Salin, Franck, Uriac, Philippe, Duca, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786041/
https://www.ncbi.nlm.nih.gov/pubmed/29374231
http://dx.doi.org/10.1038/s41598-018-20053-5