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Modulation of oncogenic miRNA biogenesis using functionalized polyamines
MicroRNAs are key factors in the regulation of gene expression and their deregulation has been directly linked to various pathologies such as cancer. The use of small molecules to tackle the overexpression of oncogenic miRNAs has proved its efficacy and holds the promise for therapeutic applications...
Autores principales: | Staedel, Cathy, Tran, Thi Phuong Anh, Giraud, Julie, Darfeuille, Fabien, Di Giorgio, Audrey, Tourasse, Nicolas J., Salin, Franck, Uriac, Philippe, Duca, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786041/ https://www.ncbi.nlm.nih.gov/pubmed/29374231 http://dx.doi.org/10.1038/s41598-018-20053-5 |
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