Novel mechanisms of Collagenase Santyl Ointment (CSO) in wound macrophage polarization and resolution of wound inflammation

Collagenases are useful in enzymatic wound debridement. Clostridial collagenase, marketed as Collagenase Santyl Ointment (CSO), is FDA approved for such use. Building on the scientific premise that collagenases as well as collagen degradation products may regulate immune cell function, we sought to...

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Detalles Bibliográficos
Autores principales: Das, Amitava, Datta, Soma, Roche, Eric, Chaffee, Scott, Jose, Elizabeth, Shi, Lei, Grover, Komel, Khanna, Savita, Sen, Chandan K., Roy, Sashwati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786052/
https://www.ncbi.nlm.nih.gov/pubmed/29374192
http://dx.doi.org/10.1038/s41598-018-19879-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786052/
https://www.ncbi.nlm.nih.gov/pubmed/29374192
http://dx.doi.org/10.1038/s41598-018-19879-w

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