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Novel mechanisms of Collagenase Santyl Ointment (CSO) in wound macrophage polarization and resolution of wound inflammation
Collagenases are useful in enzymatic wound debridement. Clostridial collagenase, marketed as Collagenase Santyl Ointment (CSO), is FDA approved for such use. Building on the scientific premise that collagenases as well as collagen degradation products may regulate immune cell function, we sought to...
Autores principales: | Das, Amitava, Datta, Soma, Roche, Eric, Chaffee, Scott, Jose, Elizabeth, Shi, Lei, Grover, Komel, Khanna, Savita, Sen, Chandan K., Roy, Sashwati |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786052/ https://www.ncbi.nlm.nih.gov/pubmed/29374192 http://dx.doi.org/10.1038/s41598-018-19879-w |
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