Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain

Heat shock protein 90 (Hsp90) is an ATP dependent molecular chaperone deeply involved in the complex network of cellular signaling governing some key functions, such as cell proliferation and survival, invasion and angiogenesis. Over the past years the N-terminal protein domain has been fully invest...

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Detalles Bibliográficos
Autores principales: Terracciano, Stefania, Russo, Alessandra, Chini, Maria G., Vaccaro, Maria C., Potenza, Marianna, Vassallo, Antonio, Riccio, Raffaele, Bifulco, Giuseppe, Bruno, Ines
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786060/
https://www.ncbi.nlm.nih.gov/pubmed/29374167
http://dx.doi.org/10.1038/s41598-017-14902-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786060/
https://www.ncbi.nlm.nih.gov/pubmed/29374167
http://dx.doi.org/10.1038/s41598-017-14902-y

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